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Irregular sleep schedules are associated with altered brain structure in youth 02/26/2026

Cool article by: Matthew Risner, Eliot S Katz & Catherine Stamoulis published in "Sleep." PMID: 41358909 DOI: 10.1093/sleep/zsaf392

Title: Social Jet lag Has Detrimental Effects on Hallmark Characteristics of Adolescent Brain Structure, Circuit Organization and Intrinsic Dynamics

The main conclusion & take home message from this study was that misaligned sleep is associated with widespread alterations in adolescent brain structures, circuit organization and dynamics of regions that play critical roles in cognitive (including social) function, and emotion and reward regulation.

Irregular sleep schedules are associated with altered brain structure in youth Many teenagers sleep in on weekends to catch up on rest. New research associates this irregular schedule with differences in the physical structure and internal communication of the developing brain, which may relate to cognitive growth.

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