Thrive with Carli

𝙄𝙩’𝙨 𝙉𝙤𝙩 𝙅𝙪𝙨𝙩 𝘼𝙗𝙤𝙪𝙩 𝙩𝙝𝙚 ☀️𝙎𝙪𝙣 — 𝙔𝙤𝙪𝙧 🧬𝙂𝙚𝙣𝙚𝙨 𝙋𝙡𝙖𝙮 𝙖 𝘽𝙞𝙜 𝙍𝙤𝙡𝙚 𝙏𝙤𝙤!

As we wrap up our Vitamin D series, let’s talk about a fascinating piece of the puzzle: genetics.

Even if you get enough sunlight and eat well, your genes can strongly influence how your body uses Vitamin D — from absorption to activation.

Here’s how 👇

1️⃣ VDR Gene (Vitamin D Receptor)
Your cells rely on this receptor to recognize and respond to Vitamin D.
➡️ Certain genetic variants make receptors less sensitive, meaning you may need higher blood levels to get the same benefits.

2️⃣ GC / DBP Gene (Vitamin D Binding Protein)
This protein carries Vitamin D through your bloodstream.
➡️ Some genotypes have lower binding efficiency, leading to less bioavailable Vitamin D — even when total blood levels look “normal.”

3️⃣ CYP2R1, CYP27B1, CYP24A1 Genes
These genes help convert Vitamin D into its active form (calcitriol).
➡️ Variants here can slow or block activation, reducing functional availability.

✨ Ethnic Insight:
Research shows that people of African descent often have lower total Vitamin D but normal bioavailable levels — thanks to genetic differences in binding proteins.
That means “low” blood levels don’t always mean deficiency in the functional sense.

✅ Takeaway:
Your Vitamin D story is personal.
If you’ve struggled to optimise levels despite good sun exposure or supplementation, genetics might be part of the reason.
Functional testing and personalised nutrition can help bridge that gap.

Next up 👉 CREATINE: The underestimated powerhouse for brain, muscle, and longevity.
We’ll unpack how this "not-just-for-bodybuilders" molecule supports brain health, hormones, muscle strength, and longevity.

✨ Thank you for joining me this month. Let’s keep building smarter, more personalised health together!

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