Cohesic
A Decision Intelligence Company | We seek cohesion across all points of healthcare data to improve clinical decisions and patient care.
06/03/2026
🫀 Can CMR help identify which patients with ICI myocarditis are most at risk for adverse cardiovascular events?
In this prospective study:
• CMR strain abnormalities were common despite preserved LVEF
• 85% met at least one Lake Louise criterion
• LA tissue characterization & strain were associated with arrhythmia, HF, and death
• Serial CMR provided additional prognostic value
As ICI use grows, comprehensive CMR may play an important role in risk stratification and follow-up.
🔗 Read the study: https://loom.ly/KU7qCl4
A newly accepted manuscript highlights the potential of accelerated dual-VENC 4D-flow MRI to improve comprehensive flow assessment in complex congenital heart disease (CHD). 🫀
In CHD imaging, clinicians often need to evaluate both high-velocity arterial jets and slow venous circulation within the same examination - a longstanding challenge for conventional single-VENC 4D-flow MRI acquisitions. Dual-VENC approaches aim to expand the measurable velocity range within a single free-breathing scan, with the potential to improve workflow efficiency and hemodynamic assessment.
In this feasibility study, the authors found that low-VENC imaging improved velocity-to-noise ratio and reduced variability in slower venous flows, while high-VENC remained necessary for accurately capturing arterial flow jets. Together, the findings support the feasibility and potential clinical utility of dual-VENC 4D-flow MRI in complex CHD.
🔗 Access more information via EHJ-IMP here! https://loom.ly/9etUXR
05/13/2026
Post hoc analysis from the European Journal of Preventive Cardiology explored whether achieved LDL-C levels after CABG are linked to saphenous vein graft (SVG) patency.
In the NEWTON-CABG CardioLink-5 trial, patients receiving evolocumab evolocumab or placebo showed no difference in overall graft outcomes. However, when looking at achieved LDL-C at 3 months, a clear pattern emerged: lower LDL-C was associated with less SVG occlusion at 2 years, independent of treatment assignment.
Each 1 mmol/L reduction in LDL-C was associated with improved graft patency (OR 0.74, P=0.005).
While post hoc, these findings reinforce a consistent message in post-CABG care—lower achieved LDL-C may translate into better graft outcomes and supports guideline-driven lipid lowering in high-risk patients!
Read the full study in the European Journal of Preventive Cardiology.
🔗 https://loom.ly/fDzuis8
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