Replenish

Saffron extract features Affron®, a 100% pure source, that has been clinically studied for mood balance in youth, young as 12 years old, adolescent and adults. Safranal, Crocin, and Picrocrocin are responsible for most of saffrons therapeutic activities. Affron saffron extract is standardized to a complex of these compounds, collectively known as Lepticrosalides.

Saffron has a calming effect on the body that helps relieve restlessness and nervousness. Daily use helps reduce symptoms of perceived stress, such as fatigue, and irritability, and improves sleep quality in people experiencing sleeplessness.

Saffron active compounds work by inhibit the reuptake mechanism of the neurotransmitters dopamine, norepinephrine, and serotonin in nerve synapses. This helps improve mood by increasing the concentration of these neurotransmitters within synapses and in the brain. Saffron also has anti-inflammatory activity that acts on the hypothalamic-pituitary-adrenal (HPA) axis, which helps lower stress hormone levels in the body.