Bioengineering Lab 434

A snapshot from a working day in the lab before holidays.
Experiments running, data taking shape, and ideas evolving through discussions.

It was also a pleasure to host our guests today — exchanging perspectives, sharing experiences, and connecting around science.

Step by step, this is how progress is made. 🔬

🧬 How can we improve enzyme immobilization in M*Fs?

Our new paper in Biotechnology Letters explores a simple but powerful idea:
modify the enzyme surface before biomimetic mineralization.

By introducing charged amino acid residues (Asp or His) onto glucose oxidase, we enhanced its interactions with Zn²⁺ and 2-methylimidazole, enabling more efficient encapsulation in ZIF-8 frameworks.

The resulting enzyme@M*F biocomposites showed:

⚡ higher catalytic activity
🧪 improved stability
🧼 stronger resistance to washing and elevated temperature

These results highlight how chemical surface engineering of enzymes can improve biomimetic mineralization and create more robust enzyme–M*F biocatalysts.

📄 Read the article:
https://doi.org/10.1007/s10529-026-03722-8

👏 Congratulations to all authors and collaborators!

⸻




*F

glucoseoxidase
biotechnology
biosensors
chemistry
scientificresearch