Immuno ICS

Interesting paper:
http://jem.rupress.org/content/early/2019/03/26/jem.20181430

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New and intersting story that may explain the role of AIRE in peripheral tolerance

Aire-expressing ILC3-like cells in the lymph node display potent APC features The autoimmune regulator (Aire) serves an essential function for T cell tolerance by promoting the “promiscuous” expression of tissue antigens in thymic epithelial cells. Aire is also detected in rare cells in peripheral lymphoid organs, but the identity of these cells is poorly understood. Here...