Generation Scotland

* Please take part in a study on a new gender-inclusive measure for ADHD *

Researchers at Cardiff University are recruiting parents & carers of children aged 9-11 (years 5 & 6) across the UK. Children don't have to have a diagnosis or even suspected ADHD - all parents/carers with children that age are invited.

* What does it involve? *
Parents/carers will be asked to complete a new gender-inclusive scale called BEARS, online or by post.

* What is the BEARS? *
BEARS stands for: Behaviour, Emotion, and Attention Regulation Scale.
BEARS was co-developed with many experts, including parents, carers, healthcare and educational professionals, and young people with lived experiences of ADHD.

* Study webpage: *
https://www.cardiff.ac.uk/wolfson-centre-for-young-peoples-mental-health/take-part/child-development-wales

Please share widely - thank you!

🧠 New research sheds light on the biological links between childhood maltreatment and depression.

Our latest study published in Translational Psychiatry explored how genetic variation in immune pathways interacts with early life trauma to shape depression risk. Here's what we found.

A huge thank you to all Generation Scotland volunteers whose generous contribution made this research possible. Studies like this simply wouldn't exist without you. 💙

🔗 Read the full paper, Herrera-Rivero et al. (2026): https://doi.org/10.1038/s41398-026-03935-5

📢New research!!

Using Natural Language Processing (NLP) on reports from routine brain scans across Scotland, researchers uncovered incidental findings that predict future disease.

A huge thank you to the volunteers of Generation Scotland, whose data made this research possible. Your contribution advances our understanding of brain health and disease prevention. 🙏

Read the full paper, Iveson et al. (2026): https://jnnp.bmj.com/content/early/2026/03/13/jnnp-2025-337689

📢New research!!

New research shows that a DNA change in the CUBN gene is linked to a higher risk of vitamin B12 deficiency in people who take metformin for type 2 diabetes. The difference is small in people who do not use metformin, but it becomes much clearer in metformin users. In UK Biobank, low B12 was seen in 12.84% of people with AA, compared with 6.02% of people with GG.

Grateful to all Generation Scotland participants whose generous contributions help make research like this possible. 💜

Read the full paper, Baldwin et al. (2026):
https://link.springer.com/article/10.1007/s00125-025-06655-5

📢New research!!

New research reveals that DNA methylation signatures of inflammation predict brain ageing better than traditional blood tests. DNAm CRP and GDF15 outperformed plasma measures in predicting cognitive decline and dementia risk over 25 years. A promising step toward identifying at-risk individuals earlier.

Grateful to all Generation Scotland participants whose generous contributions made this research possible. 💙

Read the full paper, Drouin et al. 2025: https://doi.org/10.1111/acel.70281