Path Question Bank

Another question from www.pathquestionbank.com launching 1st August with a ridiculous launch offer!

A 71-year old woman who was referred to haematology for investigation of polycythaemia returns for clinic review. At her initial appointment, there were no clear secondary causes and his Hb was
191g/l, HCT 0.56, and platelets 348 x 10^9/l. JAK2 V617F mutation analysis is negative.

Which of the following investigations is unlikely to be helpful in this situation?

A) CALR gene mutation analysis
B) JAK2 exon 12 mutation analysis
C) Abdominal ultrasound
D) Serum erythropoietin level
E) Red cell mass measurement

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