Advanced Medical Biotechnology
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15/01/2022
Title: Biodegradable Materials with Disulfide-Bridged- Framework Confine Photosensitizers for Enhanced Photo-Immunotherapy (Li et al., 2021)
Summary: When paired with Programmed cell death protein 1 (PD-1) checkpoint inhibition, SSNs@Ce6-mediated photodynamic therapy (PDT) totally eliminated 4T1 tumors. Overall, confining photosensitizers in a biodegradable disulfide-bridged framework appears to be a promising technique for unleashing photosensitizers' potential in PDT, particularly in combination cancer photo-immunotherapy.
Source: https://doi.org/10.2147/IJN.S344679
SHARED BY: Alif Haikal Elias
15/01/2022
Title: Upregulation of TMEM45A Promoted the Progression of Clear Cell Renal Cell Carcinoma in vitro (Jiang et al., 2021)
Summary: The most prevalent and dangerous type of primary kidney cancer in the world is clear cell renal cell carcinoma (ccRCC). Transmembrane protein 45A (TMEM45A) was shown to be considerably overexpressed in patients with ccRCC and resulting in poor overall and disease-free survival, poor mortality, and linked to a variety of clinicopathological criteria such as histological grade and TNM stage thus acts as a tumor promoter. Hence, it could be a viable prognostic marker and therapeutic target.
Source: https://doi.org/10.2147/JIR.S341596
SHARED BY: Alif Haikal Elias
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