Metrohm

The global fuel supply requires precise and reliable analyzers to support the many processes across the entire fuel value chain.

Find product solutions, application notes, and blog posts on the analysis of petroleum products and renewable fuel:
https://bit.ly/4uYMcrh

Accurate, reproducible results don’t happen by chance. Validating your titration method helps ensure reliability and regulatory compliance.

We recommend following the validation framework outlined in USP General Chapter and ICH Guidance Q2(R1):

✅Perform standardization of the titrant using a primary standard or a pre-standardized solution
✅Assess the accuracy and precision of the titration results by performing reference measurements
✅Verify the linearity of your results, i.e., that the titration results are proportional to the analyte concentration across the expected range
✅Demonstrate specificity, i.e., that the method can accurately measure the analyte without interference from impurities, excipients, or degradation products.

Check the link in the comment to learn more.