LOOP

Science students everywhere.

August is !

DRUG SAFETY ALERT: Drugs that are contraindicated in Breastfeeding (Note: Not all are absolutely contraindicated)

Although majority of the drugs excreted into the breastmilk are at small amounts, due to inherent vulnerability of the infant, significant adverse effects may result from inappropriate choice of medication and ill-advised drug use during breastfeeding.

Numerous factors affect the drug transfer to the breastmilk and from the breastmilk to the infant’s circulation (e.g. lipid solubility, molecular weight). Timing of the dose, drug’s toxicity, oral bioavailability, age of the infant, relative infant dose, and the volume of the milk consumed may also contribute to increased risk of toxicity to the baby.

As pharmacists, multiple therapeutic interventions can be recommended to the prescriber and patients, which ultimately reduce the risks for both the baby and mother while optimizing the benefits from breastfeeding.

Reference: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657301

Sinovac is 65.9% effective:

“In a national prospective cohort study involving 10.2 million participants in Chile, the effectiveness of an inactivated SARS-CoV-2 vaccine, which had been developed in China and administered in two doses 28 days apart, was estimated. Effectiveness among fully immunized persons was estimated at 65.9% for Covid-19 and at 87.5% for hospitalization, 90.3% for ICU admission, and 86.3% for death. https://nej.md/3qRHSdG

Original Article: Inactivated SARS-CoV-2 Vaccine in Chile”

*Laughs in calculus*