Crystallization Design Institute

The is very thrilled to welcome Rachel N. Blundell Alemán. She is a curious and driven Ph.D. graduate student whose research centers on understanding solvent solid solutions entrapped within crystalline organic molecules, with the goal of gaining greater control over materials at the molecular level. Beyond the lab, she is a Certified Medical and Community Interpreter. She enjoys playing rugby, attending raves, crocheting, and spending time with her cat. Her interests reflect both her creativity and curiosity. Always eager to learn and grow, Rachel brings enthusiasm and a knack for knowledge to everything she does. As a new member of CDI, she looks forward to contributing, collaborating, and continuing to expand her horizons. Welcome to Rachel!

We are excited to share that our latest research on solid-liquid mixing in small-scale crystallizers has been published in 𝘐𝘯𝘥𝘶𝘴𝘵𝘳𝘪𝘢𝘭 & 𝘌𝘯𝘨𝘪𝘯𝘦𝘦𝘳𝘪𝘯𝘨 𝘊𝘩𝘦𝘮𝘪𝘴𝘵𝘳𝘺 𝘙𝘦𝘴𝘦𝘢𝘳𝘤𝘩 as part of the special issue “𝘔𝘢𝘳𝘤𝘰 𝘔𝘢𝘻𝘻𝘰𝘵𝘵𝘪 𝘍𝘦𝘴𝘵𝘴𝘤𝘩𝘳𝘪𝘧𝘵” (https://doi.org/10.1021/acs.iecr.5c04538).

Although mixing is often overlooked in lab-scale crystallizers (≤100 mL), our work highlights its critical role for achieving suspension uniformity, which significantly alters the crystallization performance.
In this publication, we used computational fluid dynamics (CFD) simulations to systematically investigate the impact of stirring rate, impeller type, blade geometry and number, dual-impeller configurations, and baffles on the mixing performance.

Many thanks to all co-authors and collaborators:
Albertazzi | V. Pandit | Aprile | del Carme Pons Royo | Busini | Rota | S. Myerson | Stelzer

This work was supported by the National Science Foundation (NSF) under the Advanced Manufacturing Program (CMMI-2242255).

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Computational Fluid Dynamic Study in a Multistage Small-Scale Tower Crystallizer The solid–liquid hydrodynamics in a novel tower crystallizer consisting of seven vertically stacked spherical mixed-suspension, mixed-product removal crystallizers is reported. Mixing in spherical geometries remains underexplored. Therefore, computational fluid dynamics (CFD) simulations (Eulerian...