BnML - Behavioral & Molecular Lab

In 2018, Ana Marote, a former PhD student from BnML - Behavioral & Molecular Lab and ICVS, in collaboration with Dr Laurent Roybon’s lab at Lund University, published 3 reports in Stem Cell Research on the generation of iPSCs lines from Parkinson’s disease patients.

Find out more about these works:
https://lnkd.in/g-Qk-HT
https://lnkd.in/gWt5kTZ
https://lnkd.in/gvhANgP

For more information about these and other projects please contact us at [email protected].

Generation of an induced pluripotent stem cell line (CSC-46) from a patient with Parkinson's disease carrying a novel p.R301C mutation in the GBA gene Mutations in the glucocerebrosidase (GBA) gene have been associated with the development of Parkinson's disease (PD). An induced pluripotent stem cell…

Afinal, pode ou não o cérebro humano gerar novos neurónios durante a vida adulta? Um dos elementos da equipa BnML debate este tema num artigo de opinião, no jornal Público desta sexta-feira!

Opinião. Novos neurónios no cérebro humano adulto Afinal, tem o sistema nervoso do ser humano capacidade ou não de gerar novos neurónios ao longo da vida adulta?

Interested in how the immune system participates in the pathogenesis of anxiety disorders? Researchers from BnML - Behavioral & Molecular Lab have collaborated with researchers from University of Coimbra to explore the cross-talk between pre-natal glucocorticoid exposure, remodeling of microglial cells and development of anxiety traits. The study is now out in the prestigious journal Molecular Psychiatry, from Nature Publishing Group. To read more follow the link! http://www.nature.com/mp/journal/vaop/ncurrent/abs/mp2016173a.html

Molecular Psychiatry - Adenosine A2A receptor regulation of microglia morphological remodeling-gender bias in physiology and in a model of chronic anxiety Molecular Psychiatry publishes work aimed at elucidating biological mechanisms underlying psychiatric disorders and their treatment

Bn'ML participated in an internship program promoted by "A minha Escola de Ciências". Thank you Cristiana and Carolina for your active participation!
More info: http://amec2016ecuminho.pt/amec-nas-empresas/

A Bn'ML - Behavioral and Molecular Lab é uma Start-up da Universidade do Minho, em estreita associação com o Instituto de Investigação em Ciências da Vida e da Saúde (ICVS).

Receberá nos dias 21, 22 e 23 duas alunas, do Colégio João Paulo II e do Colégio Luso Internacional de Braga, dando-lhes a oportunidade de experimentar a investigação pré-clínica em modelos animais de doença.

Postgraduate course “Epigenetics - from mechanisms to disease” One major challenge in biology is to understand how epigenetic modifications contribute to transcriptional plasticity. This issue is of particular importance in the brain, where experience-dependent changes in gene transcription are essential for its normal activity. Indeed, loss-of-function of key…