Curia CDMO
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Curia is a global contract research, development and manufacturing organization. Learn more at CuriaGlobal.com.
07/24/2025
We’re proud to share that Dr. Vinoth Kumar, Senior Research Scientist III at Curia, and his team have had their research published in the European Journal of Organic Chemistry: “Green Approach for Copper-Free Pd-Catalyzed Sonogashira Cross-Coupling Using Saponin-Based Micellar Catalysis in Water at Ambient Temperature.” This innovation reduces EHS risks and offers a safer, more sustainable approach to chemical synthesis—advancing our commitment to green chemistry.
In the pharmaceutical industry, over 80% of organic waste comes from solvents. Dr. Kumar and his team identified Saponin, an inexpensive, biodegradable, and natural surfactant that effectively forms a micellar-catalysis system in water. This system enables a challenging C(sp2)─C(sp) coupling with a broad range of aryl/heteroaryl halides and diverse terminal alkynes at room temperature. We believe Saponin can serve as a cost-effective, long-term sustainable alternative to designer surfactants.
Read the full publication here: https://hubs.li/Q03yKJrD0
: At Curia, we bring decades of expertise and advanced technology to large-scale API manufacturing at our U.S. facilities. With the capacity to scale from 4 kg to 10 metric tons, we handle even the most complex chemistries with precision and consistency.
Our strong regulatory track record and end-to-end capabilities make Curia your trusted partner for API success, delivering quality and speed at every stage.
Watch how our manufacturing experts power breakthroughs at scale: https://ow.ly/j6kc50W3qAo
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