Ann Shippy MD

Ann Shippy MD

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Functional Medicine information and tips to improve your health She is Board Certified in Internal Medicine and Certified in Functional Medicine.

Photos from Ann Shippy MD's post 05/02/2026

Histamine intolerance is rarely just about food.
It’s about your body’s total histamine load, and your ability to clear it.

Avocado. Aged cheese. Wine. Fermented foods. Chocolate. Leftovers.

These absolutely matter, and diet is a great place to start.

But if you’ve removed these foods and you’re still not feeling well…

it’s time to look a little deeper.❤️

Histamine buildup can show up in ways that don’t always seem connected:

• Bloating, gas, or digestive discomfort
• Headaches or migraines
• Skin flushing, hives, or itching
• Nasal congestion or sinus issues
• Anxiety, irritability, or poor sleep
• Heart palpitations

These symptoms often persist when underlying drivers aren’t addressed.

Stress can suppress DAO, your primary histamine-clearing enzyme.

Poor sleep can reduce overnight histamine breakdown.
Hormonal shifts (especially estrogen) can increase histamine, and histamine can feed that cycle.

👉 Gut imbalances may lead to excess histamine production internally.

👉 Chronic infections can keep the immune system activated.

👉 Environmental toxins can interfere with both production and clearance pathways.

👉 Even dehydration can raise histamine, as the body uses it to help regulate fluid balance.

When these factors stack together, your “histamine bucket” fills faster, and symptoms follow.

Histamine intolerance is not just a food issue.
It’s a load and resilience issue.

Swipe to see more on how each of these factors can contribute

DAO is central to histamine balance. When levels are low, histamine isn’t broken down efficiently, so even small exposures can trigger symptoms.

If histamine intolerance is something you’re navigating, supporting your DAO enzyme can be a helpful tool while you address root causes.

Comment DAO, and I’ll send you the link to my Histamine Support.

Dr. Ann

Photos from Ann Shippy MD's post 04/25/2026

If you’re dealing with cravings, energy crashes, blood sugar swings, or trouble maintaining muscle, protein may be the missing piece.

Most people think protein is just for building muscle.

But it’s foundational for nearly every system in your body…from hormone production and detoxification to gut integrity, fertility, immune function, and healthy aging.

Every cell depends on amino acids as raw material for repair, resilience, and regeneration. Protein needs don’t diminish with age- if anything, the need for high-quality protein often increases.👏

Age-related muscle loss (sarcopenia) can begin as early as your 30s. Low muscle mass isn’t just a fitness issue -it’s independently linked to insulin resistance, fracture risk, immune decline, and all-cause mortality.

Protein is one of the most powerful levers you have against it.👏👏👏

A few things you may not know about protein…
Protein supports:

✔ Blood sugar balance and reduced cravings
✔ Hormone and neurotransmitter production
✔ Liver detoxification pathways
✔ Gut barrier integrity
✔ Egg and s***m quality
✔ Longevity and healthspan

Quality and consistency matter as much as quantity.

Prioritize whole food, nutrient-dense sources, and aim to distribute protein throughout the day to support muscle protein synthesis.

See slides 👆 for ways to get in more protein daily. (Paleo diet options).

I often rely on protein powder especially on busy days. My go to is Perfect Paleo Protein powder was designed to fill the gaps supporting protein intake.

Comment PALEO, and I’ll send you the link.

Dr. Ann

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