Essential Glyconutrients

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Taken together, these data suggest that D-allulose may be a useful food ingredient for the improvement or prevention of some diseases, such as chronic kidney disease.

D-allulose modulated the renal metabolomic profile, particularly of metabolites associated with both amino acid and purine metabolism in rats. Although D-allulose increased the renal weight with increasing amino acid influx, there were no changes in the plasma indices associated with renal dysfunction. Moreover, D-allulose reduced the levels of both TMAO and SDMA, which are associated with a variety of diseases, including chronic kidney and cardiovascular diseases. It should be noted that these results were obtained under limited condition of rats fasted for 3 h after a continuous intake of D-allulose. Furthermore, this study is the first study of D-allulose on renal metabolic profiling, and further studies such as measuring metabolic enzymes may further elucidate metabolic changes.

Metabolic Profiling of Rat Kidney Tissue Following Administration of D-Allulose D-Allulose (D-psicose) is a rare sugar and a C-3 epimer of D-fructose. D-Allulose has been reported to have several health benefits via its alteration …