Open Wound Research

🚨 New Publication Alert 🚨

We are excited to share that our paper:

“A Bayesian hierarchical meta-analysis of CAMPs versus standard of care for diabetic foot ulcers: Systematic review of evidence from Medicare’s 2024 final Local Coverage Determinations” https://lnkd.in/eWYzPiR2
(Authors: Zwelithini Tunyiswa, Dr. Robert Frykberg and Ryan P. Dirks)

has been published in the inaugural issue of the International International Journal of Tissue Repair.

🔍 Key insights
- Bayesian hierarchical beta-binomial model applied to randomized clinical trials cited in Medicare’s 2024 LCDs
- Standardized outcomes to 12-weeks and n = 100 (50/arm) for comparability
- Findings suggest that CAMPs may roughly double healing likelihood vs standard of care in diabetic foot ulcers
- Estimates are product- and study-adjusted, providing a quantitative benchmark for clinicians, payers, and innovators

💡 Why this matters
Diabetic foot ulcers remain one of the most costly, high-morbidity chronic complications of diabetes. Strengthening the quantitative foundation around advanced wound therapies is essential for evidence-based care, payer policy, and innovation.

👥 With gratitude
Thanks to the International Journal of Tissue Repair editorial team and reviewers for supporting rigorous, transparent wound-care research.

🙏 Open-Access Support
A special thank you to BioStem Technologies (OTC: BSEM) for supporting open-access fees to ensure this work is freely available to the wound-care community. Open access accelerates scientific equity and advances patient care — we are grateful for the partnership.

🔗 Full article
https://lnkd.in/eWYzPiR2

📂 Code & supplementary materials
To promote reproducibility and transparency, the full analysis code and data will be released on the Open Wound Research GitHub shortly.

LinkedIn This link will take you to a page that’s not on LinkedIn

Open Wound Research is proud to participate in Journal of Wound Care (JWC)'s CAMPS 2025 Wound Care Summit. Our CEO, Zwelithini Tunyiswa will be participating on a panel regarding "Optimal trial design for demonstrating evidence on product safety, effectiveness and positive clinical outcomes" with wound care leaders.