UT Southwestern Medical Center Kidney Cancer Program

Sometimes kidney cancer spreads to the pancreas — and research from Dr. James Brugarolas and team shows patients in this situation often do better than expected. Learn more here: https://doi.org/10.1172/jci.insight.195195

In metastatic renal cell carcinoma, pancreatic spread is associated with improved survival.

https://doi.org/10.1172/jci.insight.195195

Here, James Brugarolas & team determine that pancreatic arise predominantly from indolent clones within primary and exhibit distinct molecular and histological features, clinical behavior, and treatment responsiveness.

The figure shows pancreatic metastasis sample with high angiogenesis, indicated by deep learning vascular mask (red).

Happy Thanksgiving from the Kidney Cancer Program team!
Grateful for our incredible group! We celebrated with a Thanksgiving potluck filled with cultural, nostalgic, and family-favorite dishes—reflecting the diverse backgrounds that make our team so special.
🦃🍗🍁🍂

📣UT Southwestern has been ranked #1 globally among health care institutions in the biological sciences, according to the latest Nature Index (March 2024–Feb 2025).

The ranking reflects the strength and consistency of our research community, based on contributions to high-quality journals tracked by the Nature Index database.

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