Global Medical Communications GMC

Pioneering research shows that dopamine levels increase in response to stressful stimuli, and not just pleasurable ones, potentially rewriting facts about the "feel-good" hormone—a critical mediator of many psychiatric diseases. This discovery is cause to rethink treatment for psychiatric disease and addiction.

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In a "first of its kind" study, researchers also found a potential direct connection between neurodegenerative diseases, such as Alzheimer's disease, amyotrophic lateral sclerosis (ALS), glaucoma, and the herpesvirus, said Dr. Deepak Shukla, the Marion H. Schenk Esq. Professor in Ophthalmology for Research of the Aging Eye, and vice chair for research at UIC.

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We believe this can become a therapy for muscular dystrophy, including the many different forms of muscular dystrophy," said senior study author Elizabeth McNally, MD, Ph.D., director of the Center for Genetic Medicine and the Elizabeth J. Ward Professor of Genetic Medicine. "Given the success with so many other antibodies in treating chronic human diseases like rheumatoid arthritis and psoriasis, we are very optimistic this antibody can translate into the human disease setting."

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Acute decompensated heart failure (ADHF) is a life-threatening and costly disease. Controversy remains regarding the efficacy and renal tolerability of ultrafiltration for treating ADHF. The authors of this article carried out meta-analysis to evaluate this clinical issue.

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