Stem Cells Portal

The present study systematically summarizes the evidence on using all types of allogeneic cells relevant to the neonatal period in term and preterm infants from published and ongoing studies. The results show some evidence of the safety and feasibility of certain types of mesenchymal cells and highlight the lack of efficacy data for all the cell types. These findings suggest further research on a broader population of allogeneic cells is required, particularly emphasizing their efficacy related to the predominant morbidities that require therapeutic intervention in the neonatal period.

Allogeneic Cell Therapy Applications in Neonates: A Systematic Review AbstractBackground. Neonatal cell therapy applications are increasing; however, data on allogeneic cell therapy are limited.Objective. To summarize evidence on

MSCs exhibit therapeutic potential in MetS-related disorders. Gene editing, pretransplant pretreatment, and combination therapy have been applied to bolster the therapeutic potency of autologous or allogeneic MSCs.

Mesenchymal Stem/Stromal Cells Therapy for Metabolic Syndrome: Potential Clinical Application? Abstract. Mesenchymal stem/stromal cells (MSCs), a class of cells with proliferative, immunomodulatory, and reparative functions, have shown therapeutic potenti

Researchers have used heart and lung stem cells infected with SARS-CoV-2, the virus that causes COVID-19, to better understand how the disease impacts different organs. Responses varied significantly depending on the cell type, allowing the team to identify effective antiviral drugs to treat infection in these organs specifically, thus paving the way to more targeted treatment.

Stem Cells Show SARS-CoV-2's Different Effects In Heart and Lungs Researchers have used heart and lung stem cells infected with SARS-CoV-2 to find more targeted treatments for COVID-19. The virus, they find, has different effects in different cell types.

Congratulations to Dr. Jan Nolta for receiving the 2023 ISCT Career Achievement Award in Cell & Gene Therapy!
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