STG lab

New paper published in Frontiers in Cellular Neuroscience! Nelly Daur, Yang Zhang, Farzan Nadim, and Dirk Bucher show the interactions between central and peripheral spike initiation sites that shape output activity of an STG neuron. The article is part of the Research Topic “Axon Neurobiology”.

Mutual Suppression of Proximal and Distal Axonal Spike Initiation Determines the Output Patterns of a Motor Neuron Axonal spike initiation at sites far from somatodendritic integration occurs in a range of systems, but its contribution to neuronal output activity is not well understood. We studied the interactions of distal and proximal spike initiation in an unmyelinated motor axon of the stomatogastric nervous...

New Paper in eLife! Diana Martinez, Haroon Anwar, Dirk Bucher, and Farzan Nadim, in collaboration with Amit Bose from the NJIT Math Department, show how the shape of synaptic input can help to maintain the activity phase of a neuron across different frequencies of rhythmic activity.
Author manuscript is now available here:

Short-term synaptic dynamics control the activity phase of neurons in an oscillatory network In oscillatory systems, neuronal activity phase is often independent of network frequency. Such phase maintenance requires adjustment of synaptic input with network frequency, a relationship that we explored using the crab, Cancer borealis, pyloric network. The burst phase of pyloric neurons is rela...

Congratulations to Eve!

Eve Marder Known as one of the most influential neuroscientists of her generation, Marder’s research over more than 40 years has provided transformative insight into the fundamental processes of animal and human brains.

Lily Li, Dirk Bucher, and Farzan Nadim's paper about distinct rules for co-modulation of neurons and synapses is in the latest issue of the Journal of Neuroscience:
http://www.jneurosci.org/content/38/40/8549.long

Not only that, it is also a featured article, highlighted in the "This Week in The Journal" section:
http://www.jneurosci.org/content/38/40/i

Distinct Co-Modulation Rules of Synapses and Voltage-Gated Currents Coordinate Interactions of Multiple Neuromodulators Multiple neuromodulators act in concert to shape the properties of neural circuits. Different neuromodulators usually activate distinct receptors but can have overlapping targets. Therefore, circuit output depends on neuromodulator interactions at shared targets, a poorly understood process. We expl...