Aronora

Aronora is proud to share that we presented new data on AB023 and AB062 at hashtag .

AB023 is a first-in-class, Factor XI (FXI) inhibitor designed to bind the Apple 2 (A2) domain of FXI. This differentiated mechanism of action selectively inhibits Factor XII–mediated contact activation of FXI, while preserving thrombin-mediated FXI activation that supports fully functional hemostasis.

AB062 is a first-in-class, antisense oligonucleotide designed to inhibit hepatic production of thrombopoietin – a key regulator of platelet production whose signaling pathway is aberrantly activated in myeloproliferative neoplasms like essential thrombocythemia (ET).

We’re excited to hear KOLs echo our belief in the potential for Aronora's first-in-class programs to better serve patient communities at risk for life-threatening thrombosis.

Thank you to the hashtag organizers for an engaging program and we look forward to a productive year ahead!

“The venture arm is also a way for NYBC to apply its experience and capital to advance technologies for underserved areas of medicine…it is finalizing a deal to invest $2m in Aronora. A company developing drugs for blood diseases…generally raising venture capital in this field is difficult because of the perception that startups would need giant clinical studies to prove their drugs are effective in a range of patients who need anti clotting therapies…a startup can break into the market by targeting a narrower slice of the broad population… Aronora is developing its lead drug in patients on dialysis who can’t tolerate blood thinners…”

New Venture Fund Targets Innovations in Blood Research New York Blood Center and other healthcare nonprofits are using venture capital to help startups tackle diseases.

Dr. Thomas Oxley, a neurosurgeon at Mount Sinai Health System in New York, and colleagues gave details of five people they treated. All were under the age of 50, and all had either mild symptoms of Covid-19 infection or no symptoms at all.
"The virus seems to be causing increased clotting in the large arteries, leading to severe stroke," Oxley told CNN.

Covid-19 causes sudden strokes in young adults, doctors say The new coronavirus appears to be causing sudden strokes in adults in their 30s and 40s who are not otherwise terribly ill, doctors reported Wednesday.

The Contact Activation System as a Potential Therapeutic Target in Patients with COVID‐19 https://onlinelibrary.wiley.com/doi/10.1002/rth2.12349

Not all strokes look the same...

She Felt Fine, but Her M.R.I. Showed Several Strokes. What Was Wrong? After the 67-year-old woman fell at the airport, the left side of her body wouldn’t cooperate. The answer to her malady was found in her heart.