Benaroya Research Institute

Congratulations to GentiBio on this important milestone — dosing the first participant in the POLARIS trial. We’re excited to see this approach move into clinical evaluation for type 1 diabetes (T1D) 👏

This work builds on years of collaboration and discovery — including contributions from many BRI scientists led by Jane Buckner, MD, BRI president and scientific cofounder of GentiBio, alongside partners at Seattle Children's.

At BRI, we’ve long worked to understand how the immune system can be rebalanced in immune system diseases like T1D. We’re encouraged by this progress and its potential to preserve the body’s natural insulin production and improve lives.

Learn more: bri-news.short.gy/J1I295

GentiBio has successfully dosed the first participant in our clinical trial, the POLARIS Study, for adults recently diagnosed with Type 1 Diabetes (T1D). We are incredibly proud to announce this meaningful milestone for our team and community.

This achievement marks a critical step in advancing our research and would not have been possible without the dedication of the entire GentiBio team, current and former members, along with our clinical investigators, partners, and most importantly, the individuals who participate in clinical research.

Thank you to everyone who contributed their expertise and commitment to achieving this moment. We look forward to continuing the trial as we work to better understand and improve outcomes for people living with T1D.

Read the full announcement: https://www.prnewswire.com/news-releases/gentibio-announces-first-participant-dosed-in-polaris-phase-1-clinical-trial-of-gnti-122-in-recently-diagnosed-type-1-diabetes-302716586.html?tc=eml_cleartime

Learn more about the POLARIS Study: https://www.polarisstudy.com/

Rheumatoid arthritis (RA) is an autoimmune disease that affects about 1.5 million Americans — including PGA TOUR Champions professional golfer Jerry Kelly ⛳️🏌

Ahead of the 2025 Boeing Classic, BRI President and Virginia Mason Franciscan Health rheumatologist Jane Buckner, MD, sat down with Jerry to talk BRI research, life with RA, and golf.

Watch now:

Jane Buckner and Jerry Kelly Talk Research, Rheumatoid Arthritis and Golf BRI President Jane Buckner and PGA TOUR Champions Professional Golfer Jerry Kelly talk research, rheumatoid arthritis and golf ahead of the 2025 Boeing Classic.