Patient-Centered Outcomes Research Institute - PCORI

The latest edition of PCORI’s Emerging Health Care Innovation Brief features FDA approval of treatments for prostate cancer, kidney cancer and Type 1 diabetes, among others.

Other topics include:
◾ Cefepime and zidebactam (Zaynich), an intravenous antibiotic combination therapy designed to treat complicated urinary tract infections
◾Polymyxin B hemoperfusion cartridge (Toraymyxin), an external blood-filtering device intended to treat endotoxic septic shock

Read more: https://pcori.me/4guNYwt

Children with obesity may develop long-term health problems.

A PCORI-funded randomized controlled trial compared two programs within primary care to see which was more effective in promoting weight loss:
1️⃣ Enhanced standard of care: Counseling sessions with primary care clinicians
2️⃣ Enhanced standard of care plus family-based behavioral treatment: The above plus counseling sessions with trained health coaches

Read the study results to learn about the effectiveness of each program: https://pcori.me/4v2a9O4

In a PCORI-funded study, 2 approaches for treating adults with chronic migraines and medication overuse were compared.

While the 2 approaches worked about the same to reduce the number of days per month with a migraine, compared to people who continued taking the overused medicine, individuals who stopped taking the overused medicine:
◼️ Had fewer days when they used medication to relieve symptoms
◼️ Were less likely to overuse medication

These results can assist individuals and their clinicians in managing migraine pain and avoiding medication overuse. Learn more: https://pcori.me/3oRC18z

Deadline Approaching: Submit Your Input

PCORI is seeking public input on draft research questions for an upcoming systematic review: Surgical Treatment of Adults With Degenerative Lumbar Spinal Stenosis.

Deadline to provide feedback is June 29 at 5 pm (ET): https://pcori.me/4o4VsYN